What is LHON?

Leber’s Hereditary Optic Neuropathy (LHON)

In 1871, Dr. Theodor van Leber, a German ophthalmologist, described a hereditary optic neuropathy that now bears his name. LHON refers to a malfunction of the optic nerve caused by mitochondrial DNA (mtDNA) mutations, leading to rapid loss of central vision (usually in 2 to 3 months).

Onset of LHON vision loss can begin at any age.